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Review Article
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Volume 335:569-576 August 22, 1996 Number 8
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Liver Disease in Pregnancy
Tamsin A. Knox, M.D., M.P.H., and Lori B. Olans, M.D., M.P.H.

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Liver disease is a rare complication of pregnancy, but when it occurs it may do so in a dramatic and tragic fashion for both mother and infant. Diseases such as acute fatty liver of pregnancy (AFLP) may begin innocuously with mild symptoms and liver-enzyme abnormalities but, if left untreated, can progress to jaundice, liver failure, and death.

Some of the normal physiologic changes of pregnancy can mimic abnormalities associated with liver disease. In an uncomplicated pregnancy, many laboratory-test results may appear abnormal according to standards derived from a nonpregnant population. Serum albumin concentrations decrease from a mean of 4.2 g . . . [Full Text of this Article]

Cholestatic Disease

Hyperemesis Gravidarum

Intrahepatic Cholestasis of Pregnancy

Hepatocellular Disease

Viral Hepatitis

Liver Diseases of Late Pregnancy

Acute Fatty Liver of Pregnancy

Preeclampsia and Eclampsia

The HELLP Syndrome

Differential Diagnosis


Source Information

From the Gastroenterology Division, New England Medical Center Hospitals, Boston.

Address reprint requests to Dr. Knox at the New England Medical Center Hospitals, Box 103, 750 Washington St., Boston, MA 02111.

References


Related Letters:

Liver Disease in Pregnancy
Rinaldo P., Treem W. R., Riely C. A., Williams M. S., Batey R. G., Knox T. A., Olans L. B.
Extract | Full Text  
N Engl J Med 1997; 336:377-379, Jan 30, 1997. Correspondence

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