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A seven-year-old boy was admitted to the hospital because of fever, lymphadenopathy, hepatosplenomegaly, and eosinophilia.
The boy had been in good health until two months earlier, when fever and disorientation developed. He was taken to another hospital, where a seizure occurred. Meningoencephalitis was diagnosed, antibiotics were administered intravenously, and he received phenytoin and carbamazepine. He recovered and was discharged taking both agents; phenytoin was discontinued after one month.
Two weeks before admission to this hospital, the fever recurred, particularly in the early morning hours; the temperature rose as high as 38.9°C, with anorexia. Eleven days before admission, a physician found
Differential Diagnosis
Clinical Diagnosis
Dr. Jed B. Gorlin's Diagnosis
Pathological Discussion
Anatomical Diagnosis
References
Related Letters:
Case 26-1996: Hypersensitivity to Carbamazepine
Waagner D. C., Mönkemüller K. E., Jaster J. H., Levy A. M., Gleich G. J., Pichler W. J., Schnyder B., Zanni M., Gorlin J. B.
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Full Text
N Engl J Med 1997;
336:376-377, Jan 30, 1997.
Correspondence
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