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Correspondence
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Volume 335:596-598 August 22, 1996 Number 8
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Effect of Benazepril in Chronic Renal Insufficiency

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 by Klahr, S.
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 by Maschio, G.
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To the Editor: Maschio et al. (April 11 issue)1 focus their conclusions on a specific renoprotective effect of benazepril in patients with chronic renal insufficiency. However, we question whether the drug has a specific renoprotective effect, because control of both diastolic and systolic blood pressure was better in the benazepril-treated patients. In their analysis, the authors adjusted only for the difference in control of diastolic blood pressure between the benazepril and placebo groups, but Figure 3 shows that the difference in systolic blood pressure between the two groups was even greater. Several investigators have stressed the importance of aggressive control . . . [Full Text of this Article]

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