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Previous Volume 335:660-662 August 29, 1996 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The hemolytic–uremic syndrome is characterized by nonimmune hemolytic anemia, thrombocytopenia, and acute renal failure.¹ Extrarenal manifestations, particularly neurologic signs, may be present, indicating that the disease process is not limited to the kidney. As in the closely related disorder of thrombotic thrombocytopenic purpura, the pathologic hallmark of the disease is thrombotic microangiopathy. The hemolytic–uremic syndrome is the leading cause of acute renal failure in young children, but it occurs in adults as well, sometimes together with gastrointestinal infection and bloody diarrhea. Other forms of the syndrome in adults are related to pregnancy, the postpartum state, oral-contraceptive use, malignant hypertension, cancer . . . [Full Text of this Article]

References

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• Seifter, J. L., Nickeleit, V. (1997). Case 17-1997- A 67-Year-Old Woman with Vomiting, Bloody Diarrhea, and Azotemia. NEJM 336: 1587-1594 [Full Text]  
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