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Previous Volume 336:730-731 March 6, 1997 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by The Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb Investigators PubMed Citation

To the Editor: The report by the Global Use of Strategies to Open Occluded Coronary Arteries (GUSTO) IIb investigators comparing recombinant hirudin and heparin for the treatment of acute coronary syndromes (Sept. 12 issue)¹ is important and timely. Unfortunately, the study design was biased against the standard heparin treatment. The patients receiving hirudin were given loading and maintenance doses based on body weight, whereas all the patients receiving heparin were given a fixed dose, regardless of their size. Since the average weights of the patients in each group were the same, this difference in specified dosage by the protocol could . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Altman, R. (1998). Controversies in Antithrombotic Therapy in Cardiovascular Diseases. CLIN APPL THROMB HEMOST 4: 11-24 [Abstract]