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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 336:1163-1171 April 17, 1997 Number 16
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Case 12-1997— A 50-Year-Old Woman with Multiple Sclerosis and an Enlarging Frontal-Lobe Mass
David Paydarfar, and Suzanne M. de la Monte

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Presentation of Case

A 50-year-old right-handed woman with multiple sclerosis was admitted to the hospital because of an enlarging intracranial mass.

The patient had been well until 15 years earlier, when she began to have bifrontal headaches with reduced visual acuity and was found to have bilateral papilledema. A computed tomographic (CT) scan of the brain was normal. A diagnosis of pseudotumor cerebri was made, and a lumbar puncture was performed, with a gradual resolution of symptoms.

The patient was subsequently well until six years before admission, when a left footdrop developed and she began to experience numbness in the fingertips. A magnetic . . . [Full Text of this Article]

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