FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 336:1245-1247 April 24, 1997 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

The development of drugs for the treatment of Alzheimer's disease remains in its infancy. In the United States, only two drugs have been approved: tacrine, approved in 1993, and donepezil, released this year. Neither affects the underlying process that causes the loss of neurons and synapses and leads to intellectual and functional deterioration. Given the aging of our population and the tragic effects of this age-related disease, there is tremendous interest in developing treatments that will interfere with some step in the etiologic process. In this issue of the Journal, Sano et al.¹ report their experience with the use of . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Oken, B. S., Smith Doody, R. (2001). Practice parameter: Management of dementia (an evidence-based review). Neurology 57: 2323-2323 [Full Text]  
• Karlawish, J. H. T., Casarett, D. (2001). Addressing the Ethical Challenges of Clinical Trials That Involve Patients with Dementia. J Geriatr Psychiatry Neurol 14: 222-228 [Abstract]  
• Karlawish, J. H. T., Klocinski, J. L., Merz, J., Clark, C. M., Asch, D. A. (2000). Caregivers' preferences for the treatment of patients with Alzheimer's disease. Neurology 55: 1008-1014 [Abstract] [Full Text]  
• Vatassery, G. T, Bauer, T., Dysken, M. (1999). High doses of vitamin E in the treatment of disorders of the central nervous system in the aged. Am. J. Clin. Nutr. 70: 793-801 [Abstract] [Full Text]  
• Karlawish, J. H. T., Whitehouse, P. J. (1998). Is the Placebo Control Obsolete in a World After Donepezil and Vitamin E?. Arch Neurol 55: 1420-1424 [Abstract] [Full Text]  
• Yaffe, K., Sawaya, G., Lieberburg, I., Grady, D. (1998). Estrogen Therapy in Postmenopausal Women: Effects on Cognitive Function and Dementia. JAMA 279: 688-695 [Abstract] [Full Text]  
• (1997). Vitamin E and Selegiline for Alzheimer's Disease. JWatch Psychiatry 1997: 16-16 [Full Text]  
• (1997). VITAMIN E AND SELEGILINE FOR ALZHEIMER'S DISEASE. JWatch General 1997: 1-1 [Full Text]  
• (1997). Vitamin E and Selegiline for Alzheimer's Disease?. JWatch Women's Health 1997: 8-8 [Full Text]