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Paul de Kruif's Microbe Hunters, published in 1926, was already 34 years old in 1960, yet its stirring tales of discovery and heroism by the pioneers of microbiology provoked the imagination of at least one budding young microbiologist and influenced the career choices of many senior scientists practicing today. Much has happened in microbiology since 1926. At least one disease smallpox has been eradicated, and another poliomyelitis is a candidate to follow. "New" infectious agents, such as the human immunodeficiency virus and helicobacter, have appeared as if to take their place. The viral causes of many
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