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Figure 1. A 65-year-old man was admitted to our hospital with fatigue, weight loss, night sweats, and multiple pruritic erythematous nodules and plaques on his left shoulder, one of which contained two central ulcers (Panel A). Physical examination revealed hepatosplenomegaly. The diagnosis of lymphoma, suggested initially by fine-needle aspiration biopsy of one of the skin lesions, was confirmed by immunohistochemical analysis of paraffin-embedded sections of a cervical lymph node. It showed positive staining of the tumor cells with CD20 and CD79a, two cell markers of a B-cell immunophenotype (Panel B, x400), according to the alkaline phosphatase anti–alkaline phosphatase . . . [Full Text of this Article] |
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