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Previous Volume 336:1457-1458 May 15, 1997 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Drappa et al. (Nov. 28 issue)¹ discussed four patients with Fas gene mutations and associated findings that we and others have described as autoimmune lymphoproliferative syndrome,^2,3,4 a more informative name than the eponymous Canale–Smith syndrome. Our own experience with over 20 patients with the autoimmune lymphoproliferative syndrome from 13 kindreds indicates that the genetics of this process and its clinical spectrum extend well beyond that described originally by Canale and Smith or by Drappa et al. in their reanalysis of the patients of Canale and Smith.¹

The mere presence of a Fas mutation does not imply that . . . [Full Text of this Article]

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