FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 336:1519-1521 May 22, 1997 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

Half a century has passed since Alfred Jost¹ postulated that male sexual differentiation is mediated by two discrete substances produced by the fetal testis and that, in their absence, sexual differentiation proceeds to the female phenotype. During embryogenesis, fetuses of both sexes develop two pairs of genital ducts associated with the mesonephros and the undifferentiated gonads. The müllerian ducts have the potential to differentiate into the fallopian tubes, uterus, and upper part of the vagina of the female reproductive tract, whereas the wolffian ducts differentiate into the vas deferens, epididymides, and seminal vesicles of the male reproductive tract. For normal . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Rey, R. A., Codner, E., Iniguez, G., Bedecarras, P., Trigo, R., Okuma, C., Gottlieb, S., Bergada, I., Campo, S. M., Cassorla, F. G. (2005). Low Risk of Impaired Testicular Sertoli and Leydig Cell Functions in Boys with Isolated Hypospadias. J. Clin. Endocrinol. Metab. 90: 6035-6040 [Abstract] [Full Text]  
• Rey, R. A., Belville, C., Nihoul-Fékété, C., Michel-Calemard, L., Forest, M. G., Lahlou, N., Jaubert, F., Mowszowicz, I., David, M., Saka, N., Bouvattier, C., Bertrand, A.-M., Lecointre, C., Soskin, S., Cabrol, S., Crosnier, H., Léger, J., Lortat-Jacob, S., Nicolino, M., Rabl, W., Toledo, S. P. A., Bas, F., Gompel, A., Czernichow, P., Chatelain, P., Rappaport, R., Morel, Y., Josso, N. (1999). Evaluation of Gonadal Function in 107 Intersex Patients by Means of Serum Antimullerian Hormone Measurement. J. Clin. Endocrinol. Metab. 84: 627-631 [Abstract] [Full Text]