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Figure 1. A 25-year-old woman who had had a single syncopal episode two years earlier was hospitalized after a two-minute episode of syncope during an argument with a police officer over a traffic ticket. A 12-lead electrocardiogram obtained on admission showed sinus rhythm, 52 beats per minute, with a markedly prolonged QT interval of 0.68 second. Twenty-four-hour Holter monitoring in the hospital revealed recurrent asymptomatic, mostly short, episodes of torsade de pointes. One such episode occurred during sleep and degenerated into ventricular fibrillation that lasted 11/2 minutes and terminated spontaneously. At that time, the patient wrote in her diary . . . [Full Text of this Article] |