Although transplantation is the best treatment for many peoplewith end-stage renal disease, the gap between the number oforgan donors and the number of potential recipients continuesto widen.1 Patients are often treated with dialysis for yearswhile awaiting transplants, and many die.1 At the Universityof Chicago, between 10 and 20 percent of patients with availableliving donors cannot receive transplants from them because ofABO incompatibility. We propose to increase the supply of organsby using kidneys from living donors who are ABO-incompatiblewith the intended recipients but are ABO-compatible with otherrecipients. Through an exchange arrangement . . . [Full Text of this Article]
Rationale for a Paired-Kidney-Exchange Program
A Proposal for a Pilot Study
Ethical Issues
Benefits and Risks for Donors
Benefits and Risks for Recipients
Coercion and Informed Consent
The Right to Withdraw Consent
Privacy and Confidentiality
Commercialization and Exploitation
Public Acceptance
Future Possibilities
Address reprint requests to Dr. Ross at the University of Chicago, MacLean Center for Clinical Medical Ethics, 5841 S. Maryland Ave., MC 6098, Chicago, IL 60637 (e-mail: lross@uchicago.edu).
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