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Previous Volume 336:1822-1824 June 19, 1997 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Many studies have appraised the value of treatment with granulocyte colony-stimulating factor (G-CSF) or granulocyte–macrophage colony-stimulating factor (GM-CSF) in ameliorating chemotherapy-induced neutropenia. The principal aim of this treatment is to reduce the risk of infection, thereby minimizing the need for hospitalization and parenteral antibiotics. In several clinical trials, the administration of G-CSF or GM-CSF after chemotherapy did not prevent neutropenia but did shorten its duration. In some of the studies, patients treated with colony-stimulating factor had fewer febrile episodes, fewer hospitalizations, and shorter hospital stays than patients not receiving this treatment, but it had no influence on the frequency of . . . [Full Text of this Article]

References

This article has been cited by other articles:

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• Lee, S. J., Anasetti, C., Kuntz, K. M., Patten, J., Antin, J. H., Weeks, J. C. (1998). The Costs and Cost-Effectiveness of Unrelated Donor Bone Marrow Transplantation for Chronic Phase Chronic Myelogenous Leukemia. Blood 92: 4047-4052 [Abstract] [Full Text]  
• Talcott, J. A. (1997). Outpatient Management of Febrile Neutropenia: Should We Change the Standard of Care?. The Oncologist 2: 365-373 [Abstract] [Full Text]  
• Gupta, P., Welte, K., Riehm, H., Pui, C.-H., Evans, W. E. (1997). Granulocyte Colony-Stimulating Factor in Children with Acute Lymphoblastic Leukemia. NEJM 337: 1320-1321 [Full Text]