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There is extensive debate in science, ethics, and public policy about gene therapy for humans. Immersed in this literature, Walters and Palmer have coauthored a book at the leading edge of the subject. Using fine illustrations and sketches, they lucidly explain the scientific and medical background as well as the ethical issues. The quality of the book is due in part to Walters's chairing of the Working Group on Human Gene Therapy, which was created in 1984 as an arm of the Recombinant DNA Advisory Committee of the National Institutes of Health (NIH). Until 1996, when the NIH director revised
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