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Correspondence
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Volume 336:1917-1918 June 26, 1997 Number 26
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Restrictive Cardiomyopathy

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 by Kushwaha, S. S.
To the Editor: We wish to raise some points of disagreement with the description of cardiac amyloidosis by Kushwaha et al. (Jan. 23 issue)1 in their article on restrictive cardiomyopathy. The internationally accepted classification of the amyloidosis is based on the chemical nature of the deposited protein fibrils.2 Secondary amyloidosis refers exclusively to the reactive form characterized by deposition of a nonimmunoglobulin, amyloid A (AA), in association with chronic infection and inflammation (e.g., rheumatoid arthritis, inflammatory bowel disease, osteomyelitis, tuberculosis, or leprosy). The familial and senile amyloidoses are distinct entities that have never been classified as secondary and that have . . . [Full Text of this Article]

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