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Correspondence
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Volume 336:1919-1920 June 26, 1997 Number 26
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Insomnia

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 by Kupfer, D. J.
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To the Editor: In the excellent review of the management of insomnia by Kupfer and Reynolds (Jan. 30 issue),1 we read that "zolpidem may be less likely than benzodiazepines . . . to cause cognitive and psychomotor side effects (and may have fewer withdrawal effects)." It is clear that many clinicians believe this to be true, since zolpidem is the most commonly prescribed hypnotic agent in the United States.2 However, the authors cite only three studies in support of this idea, two of which did not even compare zolpidem with a benzodiazepine.

The study that did compare these drugs with . . . [Full Text of this Article]

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