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Figure 1. A painful finger ulcer (Panel A) developed in a 58-year-old man who was also found to have a palpable olecranal lymph node. The rest of his examination was unremarkable. A biopsy specimen of the lesion, fixed and sectioned thinly for transmission electron microscopy, revealed numerous parapoxvirus particles. At a low magnification, extreme swelling of infected cells can be seen, resulting in degeneration (Panel B, x6000). Higher magnification of a section of Panel B (see box) clearly shows characteristic oval virions consisting of a core (c) surrounded by an envelope (e) (Panel C, x 60,000). When questioned . . . [Full Text of this Article] |