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Previous Volume 337:1306-1308 October 30, 1997 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Viruses have caused human diseases throughout history.¹ They have developed remarkable and unique properties to help them survive. In response to the threat from viruses, the immune system has evolved two major pathways of protection, humoral (antibody) and cellular (T lymphocyte). When infection overwhelms the immune system, the result is acute disease that either ends quickly in death or becomes a chronic persistent infection. In one such battle, the human immunodeficiency virus (HIV) is still winning out over the immune system. To control this plague we must learn the answers to several questions. What are the essential elements in host . . . [Full Text of this Article]

References

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• Ikuta, K., Suzuki, S., Horikoshi, H., Mukai, T., Luftig, R. B. (2000). Positive and Negative Aspects of the Human Immunodeficiency Virus Protease: Development of Inhibitors versus Its Role in AIDS Pathogenesis. Microbiol. Mol. Biol. Rev. 64: 725-745 [Abstract] [Full Text]  
• Moyer, T. P., Temesgen, Z., Enger, R., Estes, L., Charlson, J., Oliver, L., Wright, A. (1999). Drug Monitoring of Antiretroviral Therapy for HIV-1 Infection: Method Validation and Results of a Pilot Study. Clin. Chem. 45: 1465-1476 [Abstract] [Full Text]  
• Canque, B., Bakri, Y., Camus, S., Yagello, M., Benjouad, A., Gluckman, J. C. (1999). The Susceptibility to X4 and R5 Human Immunodeficiency Virus-1 Strains of Dendritic Cells Derived In Vitro From CD34+ Hematopoietic Progenitor Cells Is Primarily Determined by Their Maturation Stage. Blood 93: 3866-3875 [Abstract] [Full Text]  
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• Kuroda, M. J., Schmitz, J. E., Barouch, D. H., Craiu, A., Allen, T. M., Sette, A., Watkins, D. I., Forman, M. A., Letvin, N. L. (1998). Analysis of Gag-specific Cytotoxic T Lymphocytes in Simian Immunodeficiency Virus-infected Rhesus Monkeys by Cell Staining with a Tetrameric Major Histocompatibility Complex Class I-Peptide Complex. JEM 187: 1373-1381 [Abstract] [Full Text]