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Previous Volume 337:124-125 July 10, 1997 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Preeclampsia continues to be a major health problem. It is a leading cause of maternal mortality in developed countries and is associated with a fivefold increase in perinatal mortality. It is now clear that preeclampsia is more than merely increased blood pressure.¹ In women with preeclampsia, perfusion to virtually every organ, including the placenta, is decreased. Activation of the coagulation cascade, increased sensitivity to any pressor agent, and increased loss of fluid from the intravascular compartment suggest dysfunction of the vascular endothelium. This is supported by a striking alteration of glomerular-capillary endothelium and increased circulating concentrations of markers of endothelial . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Lambert-Messerlian, G. M., Silver, H. M., Petraglia, F., Luisi, S., Pezzani, I., Maybruck, W. M., Hogge, W. A., Hanley-Yanez, K., Roberts, J. M., Neveux, L. M., Canick, J. A. (2000). Second-Trimester Levels of Maternal Serum Human Chorionic Gonadotropin and Inhibin A as Predictors of Preeclampsia in the Third Trimester of Pregnancy. Reproductive Sciences 7: 170-174 [Abstract]  
• (1997). DO CALCIUM SUPPLEMENTS PREVENT PREECLAMPSIA?. JWatch General 1997: 2-2 [Full Text]