Few disorders seem more confusing than autism. Common stereotypes of a severely withdrawn, mute child with ceaselesslyrepetitive activities and an averted gaze or a freakish-looking,inept, mathematical prodigy do not accurately reflectthe broad spectrum of autism. Far from being emotionally illbut otherwise normal, persons with autism are now consideredto have one of a group of developmental disorders of brain functionthat have such a broad range of behavioral consequences andseverity that they are referred to, collectively, as pervasivedevelopmental disorder (often called PDD) in the fourth editionof the Diagnostic and Statistical Manual . . . [Full Text of this Article]
Symptoms of Autism
Behavior
Communication
Play
Attention and Activities
Cognition
Sensorimotor Symptoms
Epilepsy and Autistic Regression
Prevalence
Causes
The Neurologic Basis of Autism
Course and Prognosis
Diagnosis
Intervention
Source Information
From the Saul R. Korey Department of Neurology, the Department of Pediatrics, and the Rose F. Kennedy Center for Research in Mental Retardation and Human Development, Albert Einstein College of Medicine, Bronx, N.Y.
Address reprint requests to Dr. Rapin at Rm. 807, Kennedy Center, Albert Einstein College of Medicine, 1410 Pelham Pky. South, Bronx, NY 10461.
References
Related Letters:
Autism
Longhurst J. G., Potenza M. N., McDougle C. J., Greenspan S. I., Rapin I.
Extract |
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N Engl J Med 1997;
337:1555-1557, Nov 20, 1997.
Correspondence
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[Full Text]