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Previous Volume 337:1918-1919 December 25, 1997 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Morrow, J. D. Related Article by Tardif, J.-C.

To the Editor: The report by Tardif et al. (Aug. 7 issue)¹ of the very effective reduction in the rate of restenosis after coronary angioplasty with probucol was based on the assumption that probucol may act only as a powerful antioxidant. However, a major result of the study — that probucol alone is effective, but that high-dose antioxidant vitamins themselves have no activity and, when added to probucol, may even impair the therapeutic effects of the drug — strongly argues against that basic assumption.

Probucol has a number of activities in addition to being an antioxidant, among these a lipid-lowering . . . [Full Text of this Article]

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