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Previous Volume 337:270-271 July 24, 1997 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Chronic myeloid leukemia has fascinated hematologists and others for 150 years. It was probably the first form of leukemia to be recognized as an entity in its own right; and the discoveries in this century — first of the Philadelphia chromosome, and more recently of the BCR-ABL fusion gene in leukemic cells from almost all patients with chronic myeloid leukemia — contributed substantially to our understanding of carcinogenesis in general. In the 19th century the treatment of chronic myeloid leukemia, which included solutions of arsenic trioxide and potassium arsenite,¹ was ineffective. Radiotherapy, introduced 90 years ago, provided good control of . . . [Full Text of this Article]

References

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