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Previous Volume 337:350 July 31, 1997 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Brugada et al. (March 27 issue)¹ reported the mapping of familial atrial fibrillation in three kindreds to a locus on chromosome 10q, but they did not discuss the locus on 10q for dilated cardiomyopathy with mitral-valve prolapse, which they and others have previously described.² Supraventricular dysrhythmias and dilated cardiomyopathy often segregate within the same family, apparently as a result of variable expression of a single trait.³ Mitral-valve prolapse itself is associated with ventricular and supraventricular dysrhythmias.⁴ Interestingly, two of the affected family members in the study of familial atrial fibrillation had evidence of ventricular dilatation and systolic . . . [Full Text of this Article]

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