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Images in Clinical Medicine
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Volume 337:535 August 21, 1997 Number 8
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Positive Tzanck Smear

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Figure 1.


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Figure 1. A 67-year-old man had a three-day history of pain, vesicles, and erythema of the right side of the forehead and frontal scalp, sharply demarcated at the midline. Material scraped from the floor of a vesicle was smeared on a slide and stained with Wright's stain. The diagnostic cell (x400) is the multinucleated giant cell, an epithelial cell containing numerous nuclei, nuclear molding (clustered nuclei fitted to each other's shapes), and viral inclusions that give the nuclei a homogeneous, glassy appearance. Although the Tzanck test can be positive in infections with herpes simplex, herpes zoster, and . . . [Full Text of this Article]

 



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