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Previous Volume 338:65-66 January 1, 1998 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Ibuprofen can retard the decline in pulmonary function in children with cystic fibrosis.¹ Aminoglycosides are often given to treat pulmonary infections in children with cystic fibrosis. Both ibuprofen and aminoglycosides are nephrotoxic. We have seen four children with cystic fibrosis who had transient renal failure during exacerbations of their lung disease that we believe was caused by the intravenous administration of an aminoglycoside while maintenance treatment with ibuprofen was continued.

The first patient was a 16-year-old girl with severe lung disease in whom nausea and vomiting developed six days after admission and the commencement of therapy with . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Flume, P. A., Mogayzel, P. J. Jr., Robinson, K. A., Goss, C. H., Rosenblatt, R. L., Kuhn, R. J., Marshall, B. C., and the Clinical Practice Guidelines for Pulmonary, (2009). Cystic Fibrosis Pulmonary Guidelines: Treatment of Pulmonary Exacerbations. Am. J. Respir. Crit. Care Med. 180: 802-808 [Abstract] [Full Text]  
• Smyth, A, Lewis, S, Bertenshaw, C, Choonara, I, McGaw, J, Watson, A (2008). Case-control study of acute renal failure in patients with cystic fibrosis in the UK. Thorax 63: 532-535 [Abstract] [Full Text]  
• Konstan, M. W., Schluchter, M. D., Xue, W., Davis, P. B. (2007). Clinical Use of Ibuprofen Is Associated with Slower FEV1 Decline in Children with Cystic Fibrosis. Am. J. Respir. Crit. Care Med. 176: 1084-1089 [Abstract] [Full Text]  
• Schindler, R., Radke, C., Paul, K., Frei, U. (2001). Renal problems after lung transplantation of cystic fibrosis patients. Nephrol Dial Transplant 16: 1324-1328 [Full Text]  
• Kim, H., Xu, M., Lin, Y., Cousins, M. J., Eckstein, R. P., Jordan, V., Power, I., Mather, L. E. (1999). Renal Dysfunction Associated with the Perioperative Use of Diclofenac. Anesth. Analg. 89: 999-999 [Abstract] [Full Text]  
• Oermann, C. M., Sockrider, M. M., Konstan, M. W. (1999). The Use of Anti-inflammatory Medications in Cystic Fibrosis: Trends and Physician Attitudes. Chest 115: 1053-1058 [Abstract] [Full Text]