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Correspondence
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Volume 338:761-763 March 12, 1998 Number 11
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Should Thrombolytic Therapy Be the First-Line Treatment for Acute Ischemic Stroke?

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 by The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group
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 by Caplan, L. R.
-PubMed Citation
To the Editor: Treatment of acute stroke seems to be controversial, as the Clinical Debate between Caplan et al. and Grotta (Oct. 30 issue)1,2 shows. Caplan and colleagues, on the con side, and Grotta, on the pro side, all stand firmly on the same side of the main argument — namely, that patients with acute stroke should receive aggressive treatment. In the United States today, the real alternative to therapy with tissue plasminogen activator (t-PA) is no therapy at all. Readers should not lose sight of this point in wading through the pros and cons of a specific treatment such . . . [Full Text of this Article]

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