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Previous Volume 338:992-993 April 2, 1998 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Babior and Matzner (Nov. 20 issue)¹ state that the recently identified familial Mediterranean fever (FMF) gene^2,3 can be used to establish the diagnosis of this disease. However, the penetrance of the four described mutations is not known, and patients with pyrin, or marenostrin, mutations affecting only a single allele will remain a diagnostic challenge, as illustrated by the following case report.

Recurrent fever, abdominal pain, and pleural effusions developed in a 27-year-old Armenian man. Plasma C-reactive protein concentrations exceeded 100 mg per liter during the attacks but on other occasions were normal (<10 mg per . . . [Full Text of this Article]

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