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The current debate about the causes and classification of polyarteritis and polyangiitis can be viewed from a much longer historical perspective that illuminates the problem of nosology. Glomerulonephritis is regarded as absent in classic polyarteritis nodosa, yet even Kussmaul and Maier describe hematuria and proteinuria in their index case and transient proteinuria in their second case.2 Changes of diffuse nephritis were seen at the autopsy of the first case. Kussmaul and Maier state that
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