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Figure 1. Symptoms of intermittent claudication and a painful ulceration of the right heel developed in a 50-year-old woman who smoked one pack of cigarettes per day and had diet-controlled diabetes mellitus. Her only regular medication was flurbiprofen. On examination, right pedal pulses were not palpable and there was a mottled purple discoloration of the right foot consistent with a diagnosis of livedo reticularis, with a small ulceration on the heel (Panel A). The platelet count and the partial-thromboplastin time were both normal. A skin-biopsy specimen taken from the area of ulceration showed organizing thrombi in vessels, but no . . . [Full Text of this Article] |
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