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Editorial
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Volume 338:1222-1223 April 23, 1998 Number 17
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Clearing the Cornea with Nerve Growth Factor

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 by Lambiase, A.
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In 1986 Rita Levi-Montalcini won, with Stanley Cohen, the Nobel prize for the discovery of nerve growth factor, a polypeptide they found to be integral to the growth and development of the nervous system. In her Nobel lecture reviewing 35 years of research on nerve growth factor, Levi-Montalcini stated, "The submerged areas of the NGF [nerve growth factor] iceberg loom very large."1 In this issue of the Journal, Lambiase et al. report the dramatic healing action of topically applied nerve growth factor in 12 patients (14 eyes) with neurotrophic corneal ulcers and bring into view yet another part of that . . . [Full Text of this Article]

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