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Correction to Hostetter et al., N Engl J Med 337(10):712-714 September 4, 1997.

Correspondence
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Volume 338:131-132 January 8, 1998 Number 2
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More on Anticoagulation for Continuous Hemofiltration

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 by Hostetter, T. H.
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To the Editor: Hsu et al. (Sept. 4 issue)1 describe a method of regional anticoagulation for continuous venovenous hemofiltration that involves the infusion of a citrate-containing replacement fluid. For over a year we have used a similar technique, in which a replacement fluid containing 15 mmol of disodium citrate per liter is infused at a fixed rate of 2 liters per hour, volume control is achieved by variable ultrafiltration, and the blood-flow rate is set at 60 to 150 ml per minute. This approach achieves metabolic control equivalent to that with lactate-based solutions. Correction of acidosis, however, can be insufficient . . . [Full Text of this Article]

References


Related Letters:

Continuous Hemofiltration
Hostetter T. H., Manske C. L., Paller M. S., Hsu C.-y., Palsson R., Niles J. L., van Bommel E. F.H., Grootendorst A. F., Forni L.G., Hilton P.J.
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N Engl J Med 1997; 337:712-714, Sep 4, 1997. Correspondence

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