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In 1928, Thomas Rivers edited an authoritative book entitled Filterable Viruses (Baltimore: Williams and Wilkins) that summarized virologic knowledge of the time. Leading virologists who contributed chapters included Alexis Carrel (tissue culture), Edmund Cowdry (intranuclear pathology), Harold Amos (poliomyelitis), Peter Olitsky (foot and mouth disease), and Ernest Goodpasture (fowlpox). Additional chapters were devoted to descriptions of viruses of insects, plants, and bacteria. Since that time, there have been tremendous advances in our knowledge of the large number of viruses that infect humans and the pathologic consequences of these infections, and viruses have served as tools in the discovery of many
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