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Previous Volume 338:1438-1447 May 14, 1998 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Nodular thyroid disease is common. Palpable thyroid nodules were detected in 0.8 percent of adult men and 5.3 percent of adult women in Whickham, northeast England,¹ and in 1.5 percent of men and 6.4 percent of women between 30 and 59 years of age in Framingham, Massachusetts.² In the latter population, new nodules appeared in 0.1 percent per year during a 15-year follow-up period.³ Thyroid nodules are even more commonly detected when the thyroid is examined by ultrasonography.⁴ The overwhelming majority of these nodules are benign. Several reviews describe diagnostic strategies to distinguish between benign and malignant nodules^5,6,7,8,9 or address . . . [Full Text of this Article]

Clinically Solitary Thyroid Nodules

Multinodular Goiter

Treatment of Nontoxic Uninodular Thyroid Disease

Surgery

Thyroxine Therapy

Management of Autonomously Functioning Thyroid Nodules

Treatment of Nontoxic Multinodular Goiter

Surgery

Thyroxine Therapy

Radioiodine Therapy

Adverse Effects of Suppression Therapy with Thyroid Hormone

Treatment of Toxic Uninodular and Multinodular Goiter

Antithyroid-Drug Therapy

Surgery

Radioiodine Therapy

Percutaneous Injection of Ethanol

Conclusions

Source Information

From the Department of Endocrinology, University Hospital Nijmegen, Nijmegen (A.R.H.), and the Department of Nuclear Medicine, Catharina Hospital, Eindhoven (D.A.H.) — both in the Netherlands.

Address reprint requests to Dr. Hermus at the Department of Endocrinology, University Hospital Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, the Netherlands.

References

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• (2006). Radioiodine therapy for hyperthyroidism. DTB 44: 44-48 [Abstract] [Full Text]  
• Santini, F., Pinchera, A., Marsili, A., Ceccarini, G., Castagna, M. G., Valeriano, R., Giannetti, M., Taddei, D., Centoni, R., Scartabelli, G., Rago, T., Mammoli, C., Elisei, R., Vitti, P. (2005). Lean Body Mass Is a Major Determinant of Levothyroxine Dosage in the Treatment of Thyroid Diseases. J. Clin. Endocrinol. Metab. 90: 124-127 [Abstract] [Full Text]  
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• Nieuwlaat, W.-A., Huysmans, D. A., van den Bosch, H. C., Sweep, C. G. (F., Ross, H. A., Corstens, F. H., Hermus, A. R. (2003). Pretreatment with a Single, Low Dose of Recombinant Human Thyrotropin Allows Dose Reduction of Radioiodine Therapy in Patients with Nodular Goiter. J. Clin. Endocrinol. Metab. 88: 3121-3129 [Abstract] [Full Text]  
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