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Correspondence
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Volume 338:1550 May 21, 1998 Number 21
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Fiddleheads and the International Normalized Ratio

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To the Editor: Many drugs and foods affect the response to oral anticoagulants.1 We describe a change in the international normalized ratio (INR) that was caused by the consumption of fiddleheads.

A 73-year-old man with atrial fibrillation had an INR of 1.71 on June 5, 1997. The previous four readings going back to February of 1997 had been in the therapeutic range of 2 to 3, and overall, 70 percent of the values from mid-1996 to the end of 1997 were considered to be within the therapeutic range. On extensive questioning about his food consumption during the week preceding the . . . [Full Text of this Article]

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