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Correspondence
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Volume 338:1698-1699 June 4, 1998 Number 23
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Treatment of Chronic Anal Fissure

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 by Maria, G.
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To the Editor: In the study by Maria et al. (Jan. 22 issue)1 comparing botulinum toxin and saline for the treatment of chronic anal fissure, the injection of botulinum toxin is referred to as noninvasive. Although obviously less invasive than surgery, local injection into the anal sphincter can be complicated by sepsis or impairment of continence,2 which makes the term inaccurate. Minor or transient incontinence could easily be missed at the one-month follow-up if not specifically sought. We are not told whether this outcome was included in the study, as pointed out in the accompanying editorial.3

Endoscopic anal dilation is . . . [Full Text of this Article]

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