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Previous Volume 338:1853-1854 June 18, 1998 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Acute hepatic porphyrias (acute intermittent porphyria, variegate porphyria, and hereditary coproporphyria) are inherited disorders caused by partial enzyme defects in heme biosynthesis.¹ Two retrospective studies and one case–control study have suggested an association between primary liver cancer and acute hepatic porphyrias.^2,3,4 We present data from a prospective cohort study that assessed the crude annual incidence rate of primary liver cancer in 650 French carriers of the gene for acute hepatic porphyria followed for seven years. We compared this incidence with the incidence of primary liver cancer in France using the standardized rate ratio after indirect standardization. National . . . [Full Text of this Article]

References

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• Anderson, K. E., Bloomer, J. R., Bonkovsky, H. L., Kushner, J. P., Pierach, C. A., Pimstone, N. R., Desnick, R. J. (2005). Recommendations for the Diagnosis and Treatment of the Acute Porphyrias. ANN INTERN MED 142: 439-450 [Abstract] [Full Text]  
• Kruskal, J. B., Kane, R. A. (2002). Paraneoplastic Hypoglycemia Associated With a Hepatic Hemangiopericytoma. J Ultrasound Med 21: 927-932 [Full Text]  
• Krijt, J, Stranska, P, Sanitraak, J, Chlumska, A, Fakan, F (1999). Liver preneoplastic changes in mice treated with the herbicide fomesafen. Hum Exp Toxicol 18: 338-344 [Abstract]