Developmental dyslexia is characterized by an unexpected difficultyin reading in children and adults who otherwise possess theintelligence, motivation, and schooling considered necessaryfor accurate and fluent reading. Dyslexia (or specific readingdisability) is the most common and most carefully studied ofthe learning disabilities, affecting 80 percent of all thoseidentified as learning-disabled.1 Although the diagnosis andimplications of dyslexia were once quite uncertain, recent advancesin our knowledge of its epidemiology, neurobiology, and genetics,as well as of the cognitive influences on this disorder, nowallow physicians to approach dyslexia within the framework ofa traditional medical . . . [Full Text of this Article]
Epidemiology of Dyslexia
Neurobiologic Influences
Heritability
Neurobiologic Studies
Cognitive Influences
The Phonologic-Deficit Hypothesis
Implications of the Phonologic Model of Dyslexia
Approach to the Diagnostic Evaluation
Evaluation of School-Age Children
Assessment of Reading Ability
Assessment of Intelligence
Special Considerations in Younger and Older Age Groups
Assessment at School Entry
Assessment of Bright Young Adults
Diagnosis
Management
Source Information
From the Department of Pediatrics, Yale University School of Medicine, 333 Cedar St., New Haven, CT 06510, where reprint requests should be addressed to Dr. Shaywitz.
References
Related Letters:
Dyslexia
Marshall J. C., Manilla G. T., Melhus H., Diller L. H., Shaywitz S. E.
Extract |
Full Text
N Engl J Med 1998;
338:1852-1853, Jun 18, 1998.
Correspondence
This article has been cited by other articles:
Chang, B. S., Katzir, T., Liu, T., Corriveau, K., Barzillai, M., Apse, K. A., Bodell, A., Hackney, D., Alsop, D., Wong, S., Walsh, C. A.
(2007). A structural basis for reading fluency: White matter defects in a genetic brain malformation. Neurology
69: 2146-2154
[Abstract][Full Text]
Solan, H. A., Shelley-Tremblay, J. F., Hansen, P. C., Larson, S.
(2007). Is There a Common Linkage Among Reading Comprehension, Visual Attention, and Magnocellular Processing?. J Learn Disabil
40: 270-278
[Abstract]
Schumacher, J., Hoffmann, P., Schmal, C., Schulte-Korne, G., Nothen, M. M
(2007). Genetics of dyslexia: the evolving landscape. J. Med. Genet.
44: 289-297
[Abstract][Full Text]
Hoeft, F., Meyler, A., Hernandez, A., Juel, C., Taylor-Hill, H., Martindale, J. L., McMillon, G., Kolchugina, G., Black, J. M., Faizi, A., Deutsch, G. K., Siok, W. T., Reiss, A. L., Whitfield-Gabrieli, S., Gabrieli, J. D. E.
(2007). Functional and morphometric brain dissociation between dyslexia and reading ability. Proc. Natl. Acad. Sci. USA
104: 4234-4239
[Abstract][Full Text]
Johnson, K. L., Nicol, T. G., Zecker, S. G., Kraus, N.
(2007). Auditory brainstem correlates of perceptual timing deficits.. J. Cogn. Neurosci.
19: 376-385
[Abstract][Full Text]
Dick, B. D., Kaplan, B. J., Crawford, S.
(2006). The Influence of Family History on Reading Remediation and Reading Skills in Children With Dyslexia. Canadian Journal of School Psychology
21: 106-119
[Abstract]
Banai, K., Ahissar, M.
(2006). Auditory Processing Deficits in Dyslexia: Task or Stimulus Related?. Cereb Cortex
16: 1718-1728
[Abstract][Full Text]
Hoeft, F., Hernandez, A., McMillon, G., Taylor-Hill, H., Martindale, J. L., Meyler, A., Keller, T. A., Siok, W. T., Deutsch, G. K., Just, M. A., Whitfield-Gabrieli, S., Gabrieli, J. D. E.
(2006). Neural Basis of Dyslexia: A Comparison between Dyslexic and Nondyslexic Children Equated for Reading Ability.. J. Neurosci.
26: 10700-10708
[Abstract][Full Text]
Vicari, S, Finzi, A, Menghini, D, Marotta, L, Baldi, S, Petrosini, L
(2005). Do children with developmental dyslexia have an implicit learning deficit?. J. Neurol. Neurosurg. Psychiatry
76: 1392-1397
[Abstract][Full Text]
Grizzle, K. L., Simms, M. D.
(2005). Early Language Development and Language Learning Disabilities. Pediatr. Rev.
26: 274-283
[Full Text]
Liederman, J., Kantrowitz, L., Flannery, K.
(2005). Male Vulnerability to Reading Disability Is Not Likely to Be a Myth: A Call for New Data. J Learn Disabil
38: 109-129
[Abstract]
Chang, B. S., Ly, J., Appignani, B., Bodell, A., Apse, K. A., Ravenscroft, R. S., Sheen, V. L., Doherty, M. J., Hackney, D. B., O'Connor, M., Galaburda, A. M., Walsh, C. A.
(2005). Reading impairment in the neuronal migration disorder of periventricular nodular heterotopia. Neurology
64: 799-803
[Abstract][Full Text]
Stein, M. T., Lounsbury, B.
(2004). A Child With a Learning Disability: Navigating School-Based Services. Pediatrics
114: 1432-1436
[Full Text]
Shalev, R. S.
(2004). Developmental Dyscalculia. J Child Neurol
19: 765-771
[Abstract]
Webster, R. I., Shevell, M. I.
(2004). Topical Review: Neurobiology of Specific Language Impairment. J Child Neurol
19: 471-481
[Abstract]
Lindsay, R. L.
(2004). Evidence of Functional Changes in Brains After Effective Reading Instruction. AAP Grand Rounds
12: 6-7
[Full Text]
Lishman, W A
(2003). Developmental dyslexia. J. Neurol. Neurosurg. Psychiatry
74: 1603-1605
[Full Text]
Kaminen, N, Hannula-Jouppi, K, Kestila, M, Lahermo, P, Muller, K, Kaaranen, M, Myllyluoma, B, Voutilainen, A, Lyytinen, H, Nopola-Hemmi, J, Kere, J
(2003). A genome scan for developmental dyslexia confirms linkage to chromosome 2p11 and suggests a new locus on 7q32. J. Med. Genet.
40: 340-345
[Abstract][Full Text]
Shaywitz, S. E., Shaywitz, B. A.
(2003). Dyslexia (Specific Reading Disability). Pediatr. Rev.
24: 147-153
[Full Text]
Temple, E., Deutsch, G. K., Poldrack, R. A., Miller, S. L., Tallal, P., Merzenich, M. M., Gabrieli, J. D. E.
(2003). Neural deficits in children with dyslexia ameliorated by behavioral remediation: Evidence from functional MRI. Proc. Natl. Acad. Sci. USA
100: 2860-2865
[Abstract][Full Text]
Heiervang, E., Hugdahl, K.
(2003). Impaired Visual Attention in Children with Dyslexia. J Learn Disabil
36: 68-73
[Abstract]
Amitay, S., Ben-Yehudah, G., Banai, K., Ahissar, M.
(2002). Disabled readers suffer from visual and auditory impairments but not from a specific magnocellular deficit. Brain
125: 2272-2285
[Abstract][Full Text]
Witton, C., Stein, J. F., Stoodley, C. J., Rosner, B. S., Talcott, J. B.
(2002). Separate Influences of Acoustic AM and FM Sensitivity on the Phonological Decoding Skills of Impaired and Normal Readers. J. Cogn. Neurosci.
14: 866-874
[Abstract][Full Text]
Wilson, A. M., Lesaux, N. K.
(2001). Persistence of Phonological Processing Deficits in College Students with Dyslexia Who Have Age-Appropriate Reading Skills. J Learn Disabil
34: 394-400
[Abstract]
Ben-Yehudah, G., Sackett, E., Malchi-Ginzberg, L., Ahissar, M.
(2001). Impaired temporal contrast sensitivity in dyslexics is specific to retain-and-compare paradigms. Brain
124: 1381-1395
[Abstract][Full Text]
Shalev, R. S., Manor, O., Kerem, B., Ayali, M., Badichi, N., Friedlander, Y., Gross-Tsur, V.
(2001). Developmental Dyscalculia Is a Familial Learning Disability. J Learn Disabil
34: 59-65
[Abstract]
Arkowitz, S. W.
(2000). The Overstimulated State of Dyslexia: Perception, Knowledge, and Learning. J Am Psychoanal Assoc
48: 1491-1520
[Abstract]
Ahissar, M., Protopapas, A., Reid, M., Merzenich, M. M.
(2000). Auditory processing parallels reading abilities in adults. Proc. Natl. Acad. Sci. USA
97: 6832-6837
[Abstract][Full Text]
Shaywitz, S. E., Fletcher, J. M., Holahan, J. M., Shneider, A. E., Marchione, K. E., Stuebing, K. K., Francis, D. J., Pugh, K. R., Shaywitz, B. A.
(1999). Persistence of Dyslexia: The Connecticut Longitudinal Study at Adolescence. Pediatrics
104: 1351-1359
[Abstract][Full Text]
Fulbright, R. K., Jenner, A. R., Einer Mencl, W., Pugh, K. R., Shaywitz, B. A., Shaywitz, S. E., Frost, S. J., Skudlarski, P., Todd Constable, R., Lacadie, C. M., Marchione, K. E., Gore, J. C.
(1999). The Cerebellum's Role in Reading: A Functional MR Imaging Study. Am. J. Neuroradiol.
20: 1925-1930
[Abstract][Full Text]
PERRY, C. A., RICE, R. E.
(1999). Network Influences on Involvement in the Hybrid Problem Area of Developmental Dyslexia. Science Communication
21: 38-74
[Abstract]
Zametkin, A. J., Ernst, M.
(1999). Problems in the Management of Attention-Deficit-Hyperactivity Disorder. NEJM
340: 40-46
[Full Text]
Marshall, J. C., Manilla, G. T., Melhus, H., Diller, L. H., Shaywitz, S. E.
(1998). Dyslexia. NEJM
338: 1852-1853
[Full Text]
Temple, E., Poldrack, R. A., Protopapas, A., Nagarajan, S., Salz, T., Tallal, P., Merzenich, M. M., Gabrieli, J. D. E.
(2000). Disruption of the neural response to rapid acoustic stimuli in dyslexia: Evidence from functional MRI. Proc. Natl. Acad. Sci. USA
97: 13907-13912
[Abstract][Full Text]