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Previous Volume 338:367-371 February 5, 1998 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Malaria most commonly presents as an acute systemic, febrile illness but may manifest more indolently as chronic anemia, glomerulonephritis, or tropical splenomegaly syndrome (or hyperreactive malarial splenomegaly) due to Plasmodium falciparum, P. vivax, or P. malariae.¹ Although all the major malaria parasites of humans cause acute illness that may be accompanied by splenomegaly, P. malariae is the only one recognized to cause asymptomatic infections that can last decades.¹ Asymptomatic P. malariae infections are typically associated with very low levels of parasitemia and normal physical examinations,^2,3 and they generally come to medical attention when malaria is transmitted by transfusion^2,3 or a . . . [Full Text of this Article]

Case Report

Methods

Results

Discussion

Source Information

From the Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. (J.M.V., J.L., T.F.M., D.C.K.), and the Division of Infectious Diseases, Department of Medicine, Johns Hopkins School of Medicine, Baltimore (J.M.V.).

Address reprint requests to Dr. Vinetz at the Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, 9000 Rockville Pike, Bldg. 4, Rm. 126, Bethesda, MD 20892.

References

This article has been cited by other articles:

• De Iaco, G., Saleri, N., Perandin, F., Gulletta, M., Ravizzola, G., Manca, N., Signorini, L., Matteelli, A., Prestini, K., Castelli, F. (2008). Hyper-reactive Malarial Splenomegaly in a Patient with Human Immunodeficiency Virus. Am J Trop Med Hyg 78: 239-240 [Abstract] [Full Text]  
• Collins, W. E., Jeffery, G. M. (2007). Plasmodium malariae: Parasite and Disease. Clin. Microbiol. Rev. 20: 579-592 [Abstract] [Full Text]  
• Tanomsing, N., Imwong, M., Pukrittayakamee, S., Chotivanich, K., Looareesuwan, S., Mayxay, M., Dolecek, C., Hien, T. T., do Rosario, V. E., Arez, A. P., Michon, P., Snounou, G., White, N. J., Day, N. P. J. (2007). Genetic Analysis of the Dihydrofolate Reductase-Thymidylate Synthase Gene from Geographically Diverse Isolates of Plasmodium malariae. Antimicrob. Agents Chemother. 51: 3523-3530 [Abstract] [Full Text]  
• (2002). Congenital Malaria as a Result of Plasmodium malariae--North Carolina, 2000. JAMA 287: 1520-1521 [Full Text]  
• Kulwichit, W., Rosenthal, P. J., Chadee, D. D. (2000). Malaria in a Trinidadian Man. NEJM 343: 1046-1047 [Full Text]  
• Chadee, D. D., Tilluckdharry, C. C., Maharaj, P., Sinanan, C. (2000). Reactivation of Plasmodium malariae Infection in a Trinidadian Man after Neurosurgery. NEJM 342: 1924-1924 [Full Text]  
• (1998). Record-Breaking Recrudescent Malaria Diagnosed and Cured. JWatch Infect. Diseases 1998: 14-14 [Full Text]