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Correspondence
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Volume 338:396-397 February 5, 1998 Number 6
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Confusion of Nelfinavir and Nevirapine

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To the Editor: Nevirapine (Viramune), manufactured by Roxane Laboratories, is a non-nucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. Nelfinavir (Viracept), manufactured by Agouron Pharmaceuticals, inhibits the HIV-1 protease enzyme. Unfortunately, these medications have similar generic and brand names, as well as available tablet strengths (nevirapine, 200 mg; nelfinavir, 250 mg). Therefore, the potential for drug-dispensing errors is substantial.

Within a two-week period, two patients with HIV infection presented to our outpatient HIV clinic because they were concerned about their medication. One patient, who had received a new prescription for nelfinavir (250 mg per tablet; three tablets . . . [Full Text of this Article]

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