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A 51-year-old man with refractory anemia and excess blasts in transformation was admitted to the hospital because of fever, dyspnea, and a pulmonary infiltrate.
The patient had been well until 21 months earlier, when unexplained bruising developed. Nine months before admission, mild thrombocytopenia was discovered on evaluation for arthroscopic surgery. Laboratory tests were performed (Table 1). Microscopical examination of a bone marrowbiopsy specimen revealed normocellular marrow with dyserythropoiesis and dysmegakaryocytopoiesis. The patient received no treatment. Five and a half months before admission, laboratory tests were performed (Table 1). Two months later, the patient returned to the
Differential Diagnosis
Clinical Diagnoses
Dr. Gerard B. Hayes's Diagnoses
Pathological Discussion
Anatomical Diagnoses
References
Related Letters:
Case 5-1998: Bone Marrow Blasts in Chronic Myelomonocytic Leukemia
Bennett J. M., Hayes G. B.
Extract |
Full Text
N Engl J Med 1998;
338:1925-1926, Jun 25, 1998.
Correspondence
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