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Volume 339:693-698 September 3, 1998 Number 10
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Capturing the Unexpected Benefits of Medical Research

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Remarkable advances have been made recently in our understanding of the molecular and genetic bases of disease. The potential therapeutic opportunities offered by these scientific findings, combined with the expanding needs of an aging population, have led to broad-based congressional support for increases in the National Institutes of Health budget. These developments have put into sharp relief the question of how to allocate growing budgetary resources among the various categories of medical research. In addition to the need to support basic-science research, investigators and policy analysts alike have recently emphasized the need to invest in translational research and clinical evaluative . . . [Full Text of this Article]

Why Uncertainty Endures

The Post-Innovation Innovation Process

Policy Implications

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