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Previous Volume 339:771-772 September 10, 1998 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Connolly, H. M. Related Article by Artlett, C. M. PubMed Citation

To the Editor: Artlett et al. (April 23 issue)¹ put forward the provocative hypothesis that systemic sclerosis may be caused by a graft-versus-host–like reaction induced by retained fetal cells in the mother. Although the hypothesis is intriguing, the occurrence of systemic sclerosis in men and nulliparous women clearly indicates that antimaternal reactions are not the sole basis of the disease. Furthermore, we believe that the similarities between graft-versus-host disease and systemic sclerosis are outweighed by considerable differences that make the two entities readily distinguishable.

Fibrosis occurs in only a minority of patients with graft-versus-host disease, develops late in the course . . . [Full Text of this Article]

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