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Previous Volume 339:848-849 September 17, 1998 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The results of AIDS Clinical Trials Group Study 243, reported by Hall et al. (May 7 issue),¹ show that neither cytarabine nor regimens of one or two reverse-transcriptase inhibitors affect the course of progressive multifocal leukoencephalopathy in patients infected with the human immunodeficiency virus (HIV). Recent case reports have indicated that neurologic conditions and survival may improve in patients with progressive multifocal leukoencephalopathy who receive highly active antiretroviral therapy, including protease inhibitors.^2,3,4 Protease inhibitors became widely available only after the cytarabine trial.¹

We evaluated survival and the presence or absence of JC virus DNA in cerebrospinal fluid . . . [Full Text of this Article]

References

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Central Nervous System Depression after Ingestion of RenewTrient
Olson K. R., Dyer J. E., Haller C., Nelson L. S., Howland M. A., Hoffman R. S.
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N Engl J Med 1999; 340:570, Feb 18, 1999. Correspondence

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