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A colleague of mine, after attending a lecture on bone disease, remarked that the vitamin D pathways looked just like chicken wire an apt observation, because it emphasizes that this "vital amine" is actually a steroid hormone with complex metabolism and multisystemic effects. Vitamin D, a new textbook edited by Feldman, Glorieux, and Pike, has enough chicken wire to fence in a farm, but most of it is very interesting. There are about 30 naturally occurring metabolites of vitamin D and more than 800 synthetic analogues designed to treat a variety of diseases, ranging from rickets to cancer. A
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