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Figure 1. A 24-year-old man with the acquired immunodeficiency syndrome presented in May 1997 with proteinuria and renal insufficiency. The most recent assessment of viral burden revealed a human immunodeficiency virus (HIV) type 1 RNA level of 62,000 copies per milliliter. In September 1996, Cryptococcus neoformans infection had been diagnosed on the basis of blood and cerebrospinal fluid cultures (cerebrospinal fluid findings: glucose, 55 mg per deciliter [3.1 mmol per liter]; protein, 17 mg per deciliter; 6 red cells; and 0 white cells). The patient received a cumulative dose of 4.5 g of intravenous amphotericin B but declined maintenance . . . [Full Text of this Article] |