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Review Article
Drug Therapy
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Volume 339:1298-1307 October 29, 1998 Number 18
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Medical Management of Glaucoma
Wallace L.M. Alward, M.D.

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Glaucoma is the leading cause of irreversible blindness in the world. It is estimated that by the year 2000, 66.8 million people will be affected, of whom 6.7 million will be blind in both eyes.1 Glaucoma is an optic neuropathy in which the axons of the optic nerve die and the plates of lamina cribrosa collapse, leading to loss of optic-nerve tissue and excavation, or "cupping," of the ophthalmoscopically visible optic-nerve head. When sufficient axonal loss occurs, peripheral vision declines; loss of central vision occurs much later. Most forms of glaucoma are painless, and the loss of vision is insidious.

Diagnosis

. . . [Full Text of this Article]

Treatment

{beta}-Adrenergic–Antagonist Drugs

Prostaglandin Analogues

Adrenergic-Agonist Drugs

Carbonic Anhydrase Inhibitors

Cholinergic Agonists

Cannabinoids

New Drugs

Conclusions


Source Information

From the Glaucoma Service, Department of Ophthalmology, University of Iowa College of Medicine, 200 Hawkins Dr., Iowa City, IA 52242, where reprint requests should be addressed to Dr. Alward.

References


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