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Review Article
Current Concepts
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Volume 339:1376-1381 November 5, 1998 Number 19
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Management of Nonulcer Dyspepsia
Robert S. Fisher, M.D., and Henry P. Parkman, M.D.

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The term "dyspepsia," derived from the Greek words dys (bad) and pepsis (digestion), refers to symptoms thought to originate in the upper gastrointestinal tract.1,2 Dyspepsia is often used to refer to upper abdominal pain or discomfort but may also encompass symptoms of early satiety, postprandial abdominal bloating or distention, nausea, and vomiting.2,3 Dyspepsia can be episodic or persistent and is often exacerbated by eating. The prevalence of dyspepsia ranges from 26 percent in the United States to 41 percent in England.4,5 Although only 20 to 25 percent of persons with dyspepsia seek medical care, the problem is responsible for 2 . . . [Full Text of this Article]

Differential Diagnosis of Dyspepsia

Diagnosis of Nonulcer Dyspepsia

Theories of Pathogenesis

Nonmotility Disorders

Motility Disorders

Treatment

Gastric Acid–Suppressing Agents

Prokinetic Agents

Treatment of H. pylori Infection

Psychotropic Medications

Antinociceptive Agents

Evaluation and Choice of Treatment

Role of Endoscopy

Empirical Therapy

Summary


Source Information

From the Gastroenterology Section, Department of Medicine, Parkinson Pavilion, 8th Fl., Temple University School of Medicine, 3401 N. Broad St., Philadelphia, PA 19140, where reprint requests should be addressed to Dr. Fisher.

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