To the Editor: Troglitazone is an antidiabetic drug that decreaseshyperglycemia by increasing the sensitivity of peripheral tissueto insulin.1 Its most serious adverse effect is hepatic dysfunction,which occurs in a small percentage of patients.2 We describea case of pleuritis in a patient who was treated with troglitazone.
The patient was a 47-year-old man who had been treated for hypertensionand type 2 diabetes mellitus with slow-release nifedipine andglyburide, respectively. He had smoked 1 1/2 packs of cigarettesdaily for 18 years but had stopped 10 years earlier. He hadno history of drug allergy or occupational . . . [Full Text of this Article]
References
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(2005). Intrarenal arterial aneurysms with haematuria in a patient with tuberous sclerosis complex. Nephrol Dial Transplant
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Aleo, M. D., Lundeen, G. R., Blackwell, D. K., Smith, W. M., Coleman, G. L., Stadnicki, S. W., Kluwe, W. M.
(2003). Mechanism and Implications of Brown Adipose Tissue Proliferation in Rats and Monkeys Treated with the Thiazolidinedione Darglitazone, a Potent Peroxisome Proliferator-Activated Receptor-{gamma} Agonist. J. Pharmacol. Exp. Ther.
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