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Correspondence
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Volume 339:1400 November 5, 1998 Number 19
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Pleuropulmonary Disease in a Man with Diabetes Who Was Treated with Troglitazone

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 by Imura, H.
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 by Salama, A. D.
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To the Editor: Troglitazone is an antidiabetic drug that decreases hyperglycemia by increasing the sensitivity of peripheral tissue to insulin.1 Its most serious adverse effect is hepatic dysfunction, which occurs in a small percentage of patients.2 We describe a case of pleuritis in a patient who was treated with troglitazone.

The patient was a 47-year-old man who had been treated for hypertension and type 2 diabetes mellitus with slow-release nifedipine and glyburide, respectively. He had smoked 1 1/2 packs of cigarettes daily for 18 years but had stopped 10 years earlier. He had no history of drug allergy or occupational . . . [Full Text of this Article]

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