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Correspondence
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Volume 339:126-127 July 9, 1998 Number 2
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Nisoldipine and Myocardial Infarction

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 by Estacio, R. O.
To the Editor: Estacio et al. (March 5 issue)1 report an increased incidence of fatal and nonfatal myocardial infarction in patients with hypertension and diabetes who received nisoldipine, in a randomized, prospective, blinded study of moderate as compared with intensive control of hypertension and nisoldipine as compared with enalapril. The increased incidence of fatal and nonfatal myocardial infarction could be due to a deleterious effect of nisoldipine, a protective role of enalapril, or both, but the study design does not allow for further conclusions. Since, as the authors state, the incidence of myocardial infarction in the nisoldipine group was not . . . [Full Text of this Article]

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